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CoQ10 could potentiate both the antiarthritic and the antioxidative effect of MTX, evident by the decreased levels of protein carbonyls in plasma and levels of 4-HNE adducts and MDA adducts to plasma proteins [175]

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Another enzyme, with similar activity to that of folate hydrolase 1, is called γ-glutamyl hydrolase (also known as conjugase or folate conjugase)